Tamarisk’s Oral Insulin

Updates from the Lab

May 2016 Update:  Oral Insulin Delivery

LOS ANGELES, April 25, 2016 /PRNewswire/ — Tamarisk Technologies Group, LLC, a technology development company engaged in the development of innovative drug delivery technology, announced today remarkable oral insulin bioavailability results from a recent diabetic rat study conducted by Charles River Laboratories of Shrewsbury, MA. In the study, orally dosed insulin carried within Tamarisk’s novel MxBA™ delivery platform resulted in an astounding relative bioavailability of *54% compared to the subcutaneous insulin administered controls. This study confirms GI sensitive biological molecules, among other more robust drugs, can be protected and delivered to the systemic circulation in therapeutic quantities utilizing Tamarisk’s novel MxBA™ oral delivery platform.

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“The results of this study set a new paradigm in the oral delivery of proteins and peptides, such as insulin,” says Dean Crowell, Executive Director of Tamarisk Technologies Group.  “As we always suspected, oral delivery of biological molecules requires a highly engineered delivery mechanism to overcome the many hurdles of GI absorption. Combining today’s results with those of previous studies, we have shown the highly engineered MxBA™ oral delivery platform effectively increases the bioavailability of a growing list of payloads.”

“Dramatic results, like what we are seeing from independently conducted animal studies, including the one announced today, certainly validate the MxBA™ oral delivery platform as a novel technology that will benefit millions of patients currently on injectable biologic therapies. The implications of this technology for healthcare are immense and will revolutionize the drug delivery market,” says A.T. Snoots, Tamarisk’s Director of Operations.

Tamarisk’s leadership will be available at the 2016 BIO Conference in San Francisco in early June to share firsthand some of our exciting news and discuss new partnering opportunities.

* Excludes 2 study responders that had time-point plasma insulin levels that exceeded detection limits.

Tamarisk’s MxBA Oral Drug Delivery System opens new avenues of development for new drug technologies in the 21st century. Let Tamarisk custom design an oral delivery experience for you second to none.

  • Proof of concept test samples can be readily manufactured
  • No additional complex synthesis
  • High encapsulation efficiency
  • Biologic or small molecule capable
  • Hydrophobic or hydrophilic APIs
  • Lab-scale operation ready to go
  • Analytical testing and method development services available

Why Oral Insulin Doesn’t Work – Click Here

For more information contact us at info@tamarisktechgroup.com or call 702.516.6451.

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